Tag: depression

A condition called Pyrrole Disorder

Hello all Scott here again.

Following on from my last post I thought I would talk about something called “Pyrrole disorder” or Pyroluria.

So what is pyrrole disorder?

Pyroluria, or pyrrole disorder, is a condition caused by stress. It develops when there are too many pyrrole molecules in your body.

Hydroxyhemopyrrolin-2-one (HPL) is a molecule naturally excreted via urine. Some people may excrete more HPL (pyrroles) than others. Previously called elevated HPL, this condition is now known as pyrrole disorder.

Pyrrole molecules don’t serve any important function in the body. However, an excessive amount can deplete the body of certain vitamins and minerals before they are able to be absorbed.

This means that these nutrients, mostly zinc and B6, become depleted in the body. This in turn leads to an excess of copper because copper and zinc are linked and the levels of one affect the other.

The result of this is noticeable shifts in mood.

Pyrrole disorder has been known to have symptoms including anxiety, depression and even schizophrenia.

How is it diagnosed?

The condition has many and varied signs and symptoms, making it impossible to diagnose from history and observation alone. It is often mistaken for bipolar disorder. This is due to the variations of mood changes, which can range from mania to depression over a period of weeks.

There is also pathology testing which includes a urine assessment called a kryptopyrrole test. This test identifies how many HPL molecules you have in your body. An excessive amount may indicate pyrrole disorder.

What are some common symptoms?

This disorder is thought to affect around 10% of the population with the most likely cause being genetics.

Common symptoms include –

  • sensitivity to light or sound
  • irritable bowel syndrome
  • mood swings / a propensity to anger easily for insufficient reason
  • memory loss / poor short-term memory
  • feelings of anxiety / depression
  • Insomnia / fatigue

The severity of symptoms can be affected by stressful or traumatic situations and/or poor diet as well as allergies.

How is it treated?

Research on this subject is still ongoing and new things are being discovered about it all the time.

At this stage there appears to be no cure as such for Pyrrole disorder. However, given the role of HPL molecules in removing vitamin B6 and zinc from the body, it has been found that supplementing these micronutrients can help treat pyrrole disorder.

Most therapies focus on a holistic approach that addresses nutrition, stress, and lifestyle.

I hope you found this information interesting.

Till the next post,

Live clean n prosper

 (Sources – Nutrient Power  by Dr William J. Walsh,  The Science of Psychotherapy )

Mood Disorders and the Gut

HI, Scott here. While I am on holidays from UNI I have decided to write a post for our blog.

Since my studies are focused on treating anxiety, depression and PTSD what better subject to start with.

None of these conditions are simple or simple to treat. First is to identify which mood disorder followed by identifying the cause.

There are many reasons people suffer from a mood disorder. It may have been triggered by a traumatic experience or a result of poor dietary practices. Trauma does not need to be a specific event. It could be a result of a series of things that have built up to have a cumulative effect. Just as diet doesn’t need to be recent, it could be that a persons diet as a child was lacking which has had long lasting effect the body.

So, what to do about it,

My belief is that a multi-pronged approach is needed. This will mean lifestyle and diet changes with the addition of some specific, medicinal herbs and counselling.

For some it may also mean accepting that things will not be the same as they were before. When we say “I just wish that I could be the way I was when” this may not be possible simply because life changes us every day we live it. Equally, this does not mean that we need to go through life suffering or causing pain to those who love us.

The body is an amazing thing that conventional medicine thinks of as a machine but in my view is so much more than that.

The way the bodies systems work with each other, is like a giant 3D jigsaw that is in constant motion. Its just incredible to think that it is continually changing shape, growing and shedding all the time. This also means that by giving the body what it needs actually helps the body and mind to heal itself.

How does this work?

Primarily, the work is done in the gut or microbiome. This process is truly fascinating and has become my passion.

There are many scientific papers that discuss the importance of the microbiome and its effect on our mood and personality. A 2016 article in “The Canadian Journal of Psychiatry” looks at the influence of the microbiota on the development of PTSD with some interesting results. By looking at how gut bacteria produce neurotransmitters like Serotonin, Dopamine and GABA.

Put simply, what we eat directly affects the structure and function of the brain and, ultimately, our mood. Few people are aware of the connection between nutrition and depression. It is easier to understand the connection between nutritional deficiencies and physical illness.

Depression is more typically thought of as strictly biochemical or emotionally based. However, science has discovered that nutrition can play a key role in the onset as well as severity and duration of depression. There are actually more neurotransmitters produced in the gut than in the brain.

Like an expensive car, the brain functions best when it gets only premium fuel. Eating high-quality foods that contain lots of vitamins, minerals, and antioxidants nourishes the brain.

Diets high in refined sugars, for example, are harmful to the brain. Multiple studies have found a correlation between a diet high in refined sugars and impaired brain function and a worsening of symptoms of mood disorders.

What does all this mean for people suffering with a mood disorder?

It means when reaching for that soft drink, cheeseburger or deep fried snack. Take a moment to think about your mental health and the effect that your diet may have on it.

Identifying a diet that has a positive effect on mental health is a whole other subject, however, a whole food diet is going to be most beneficial. This means that if you can’t identify what you are eating, chances are it’s not doing you, or your mental health any favours.

Till the next post,

Live clean n Prosper

(Sources –
The Canadian Journal of Psychiatry & Neuroscience –
Harvard Medical School – 
US National Library of Medicine, National Institute of Health )

Vitamin D, Sunlight & Mushrooms

Today’s topic is Vitamin D, Sunlight & Mushrooms.

I know that this seems like a strange combination but all will become clear.

This morning I read an article about vitamin D deficiency. It seems that despite Australians being referred to as ‘bronzed aussies’ and our nation referred to as a ‘sunburnt country’, many Australians are actually deficient in this vitamin.

Many Australians work predominantly indoors and spend much of their leisure time indoors. This limits overall sun exposure.

The awareness of skin cancer and the increasing use of sun screens also mean that our bodies don’t absorb the necessary rays required to create vitamin D from sunlight.

What is Vitamin D?

It is a hormone that helps the body absorb calcium and control calcium levels in the blood. It is also important for preventing depression, muscle growth, organ development and supporting the immune system.

Recent research suggests adults may actually need at least 2,000 IU of vitamin D every day to maintain a healthy level in the body and reap the most benefits.

Most living things can make vitamin D through sunlight exposure.

The human body is able to produce its own vitamin D3 when the skin is exposed to the sun’s ultraviolet (UVB) rays. When UVB rays hit the skin, a chemical reaction happens: The body begins the process of converting a prohormone in the skin into vitamin D3.

It’s estimated that we should get more than 90% of our vitamin D from daily sun exposure.

The amount of vitamin D absorbed from sunlight depends on some variables, including the country and skin pigmentation. Under picture-perfect conditions, the human body is able to produce as much as 10,000 IU to 20,000 IU of D3 in just 30 minutes

Studies have found that between 2 to 15 minutes of sun exposure to your unprotected face, arms, legs or back, three to four times every week is enough for your body to produce all the D3 it needs. Times will vary depending on the time of year and where you live. (Source – ABC Health)

Where do the Mushrooms come in?

Research has found that we can get a small amount of vitamin D from food. Fish and eggs naturally have some vitamin D, while some processed foods have added vitamin D.

Mushrooms also have a small amount of Vitamin D. The form of D vitamin produced in mush­rooms is D2, unlike the D3 found in the few animal foods that naturally contain it.

It used to be thought that D2 was less potent and bioavail­able in the body than D3. A recent study comparing D2 from mushrooms with D3 from supplements, has found that D2 is as effective as D3 in boosting the biologically active form of the vitamin in the body.

It is also possible to boost the levels in mushrooms by putting them in the sun for a while.

Just 15 minutes of direct sun­light can produce 200 to 800 IU in 85 grams of mushrooms regardless of type. At least 90% of the vitamin is retained after storage and with cooking.

To do this your­self, place the mushrooms with the “gills” (or underside) facing the sun to increase D production. The mush­rooms may discolour or dry out a little.

If you like mushrooms, exposing them to UV can help you get more vitamin D, however you have to eat a lot. They will certainly boost your levels and add other nutritional elements to your diet. Most of us probably find it’s easier to take a vitamin D3 supplement.

Till the next post,

Live Clean n Prosper